Review of Treatments for Oropharyngeal Fungal Infections in HIV/AIDS Patients

HIV and AIDS patients are susceptible to opportunistic infections. Oral candidiasis or thrush is the primary manifestation of fungal infection in these patients. The objective this literature review was summarize established novel treatment options for oropharyngeal infections HIV/AIDS Azoles polyenes two antifungal drug classes employed oral candidiasis. A conducted on Medline Google Scholar October 2021 using keywords “Oral”, “Fungal”, “HIV”, “Treatment”. Included studies were clinical trials, meta-analyses, randomized controlled trials. Nineteen regarding azoles, polyenes, treatments examined review. concern demonstrated from increased reports resistance antifungals, especially development fluconazole resistance. Additionally, that had different relapse durations comparative other medications, posaconazole could possibly act as an alternate form treatment. Nystatin indicated a first-line therapy multiple but be upstaged by miconazole nitrate resource-poor settings. Amphotericin B effective option shown resilient terms resistance, however potent adverse side effects reported. Alternative treatments, such immunoglobulin antibodies lemon grass, revealed promising immunocompromised individuals. Taken together, provides thorough summary